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Fast & Gentle

Microfluidic Fluorescence-Activated Single Cell Dispenser

Dispense into 96-well plate in 1 min / 384-well plate in 6 mins

 
 
Pala™ 2 lasers - up to 11 colors

Many Applications...


Rapid Cell Cloning
Antibody Discovery
CRISPR and Cell Engineering
Single Cell Genomics
Cell Line Development

Redefining Single Cell Isolation

FACS - Harsh, difficult
Harsh, difficult
Pala™ - Fast, gentle, easy
Fasy, Gentle, Easy
Pipetting - Slow, difficult
Slow, difficult
  • High pressure,
    liquid shear induced cell stress
  • Difficult to operate
    • Clogging
    • Cross-contamination
    • Drop delay adjustment & bead calibration
  • Time-consuming
  • Requires large sample material
  • High maintenance & running costs
  • Fast: 96-well plate in 1 min / 384-well plate in 6 mins
  • Gentle: Low pressure, healthier cells
  • Easy to use: No cross-contamination
  • Combat & Mobile: Generates low liquid waste
  • Poisson distribution
  • Poor efficiency
  • Poor reliability
  • Time-consuming
  • High wastage of plastics

Pala Single Cell Dispensers vs Conventional Cell Sorters

See how Pala compares with fluorescence-activated cell sorting (FACS)
Pala Cell Select Single Cell Dispensers Conventional Cell Sorters
Pressure Less than 2 psi 20 - 70 psi
Initiation time 2 - 3 min 30 - 45 min
Processing speed 2 - 50,000 cells/second 2,000 - 20,000 cells/second
Fluorescence channels Up to 11 16
Minimum input 100 cells 200,000 cells
Droplet size 1 μL 0.001 - 0.005 μL
Sheath 6.5 mL/hr 1 - 2 L/hr
Sterile sorting Easy Difficult
96-well sorting Standard Optional
System clogging No Yes
 

How it works?

 

Testimonials from your Peers for Cell Sorting and Single Cell Dispensing

Accelerate the Development of CRISPR-Edited Cell Line Models Using Bio-Techne Single Cell Dispensers

Posted 20 May 2024
Utilizing this machine [the Bio-Techne Single Cell Dispenser] has proven instrumental in streamlining the development process of single-cell clones for the cell lines I am working on. It has greatly facilitated the generation of valuable research tools, contributing to the overall progress and efficiency of my work.
- Dr. Oscar Perez-Leal, MD, Assistant Professor, Temple University, School of Pharmacy

Trusted by Leading Institutions


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